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已发表论文
脂肪肉瘤的靶向治疗的研究进展
Authors Guan Z, Yu X, Wang H, Wang H, Zhang J, Li G, Cao J, Teng L
Published Date January 2015 Volume 2015:8 Pages 125—136
DOI http://dx.doi.org/10.2147/OTT.S72722
Received 14 August 2014, Accepted 11 November 2014, Published 5 January 2015
Abstract: Liposarcoma (LPS) is the most common type of soft-tissue sarcoma.
Complete surgical resection is the only curative means for localized disease;
however, both radiation and conventional cytotoxic chemotherapy remain
controversial for metastatic or unresectable disease. An increasing number of
trials with novel targeted therapy of LPS have provided encouraging data during
recent years. This review will provide an overview of the advances in our
understanding of LPS and summarize the results of recent trials with novel
therapies targeting different genetic and molecular aberrations for different
subtypes of LPS.
Keywords: well-/dedifferentiated, myxoid/round cell, pleomorphic, soft-tissue sarcoma
Keywords: well-/dedifferentiated, myxoid/round cell, pleomorphic, soft-tissue sarcoma
